SENP1 anticorps (AA 19-619)

N° du produit ABIN7600423

L’anticorps anti-SENP1 Monoclonal Souris est utilisé pour la détection de SENP1 dans des échantillons de Humain. Il a été validé pour WB et FACS.

Aperçu rapide pour SENP1 anticorps (AA 19-619) (ABIN7600423)

Antigène: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SENP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 5F4

Détail du produit anti-SENP1 anticorps

Épitope: AA 19-619

Fonction: Anti-SENP1 Antibody (monoclonal, 5F4)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SENP1 Antibody (monoclonal, 5F4) (ABIN7600423). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SENP1 recombinant protein (Position: N19-P619).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SENP1

Antigène: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Autre désignation: SENP1

Sujet:

Synonyms: Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19

Tissue Specificity: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

Background: Sentrin-specific protease 1 is a protein that in human is encoded by the SENP1 gene. This gene is mapped to 12q13.11. This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 73 kDa

ID gène: 29843

UniProt: Q9P0U3

Pathways: Positive Regulation of Endopeptidase Activity