Poliovirus Receptor anticorps (AA 24-345)

N° du produit ABIN7600826

Cet anticorps anti-Poliovirus Receptor Polyclonal Lapin (ABIN7600826) détecte spécifiquement Poliovirus Receptor dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour Poliovirus Receptor anticorps (AA 24-345) (ABIN7600826)

Antigène: Poliovirus Receptor (PVR)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Poliovirus Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Poliovirus Receptor anticorps

Épitope: AA 24-345

Fonction: Anti-Poliovirus Receptor/PVR Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Poliovirus Receptor/PVR Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Poliovirus Receptor/PVR recombinant protein (Position: R24-R345).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Poliovirus Receptor

Antigène: Poliovirus Receptor (PVR)

Autre désignation: PVR

Sujet:

Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PVR cell adhesion molecule

Poids moléculaire: 60-80 kDa

ID gène: 52118

UniProt: Q91WP1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome