RNASEH2A anticorps (AA 25-299)
Aperçu rapide pour RNASEH2A anticorps (AA 25-299) (ABIN7600899)
Antigène
Voir toutes RNASEH2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 25-299
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Fonction
- Anti-Ribonuclease H2, subunit A/RNASEH2A Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Ribonuclease H2, subunit A/RNASEH2A Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Ribonuclease H2, subunit A/RNASEH2A recombinant protein (Position: R25-L299).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
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Autre désignation
- RNASEH2A
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Sujet
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Background: Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.
Gene Full Name: ribonuclease H2 subunit A
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Poids moléculaire
- 33 kDa
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ID gène
- 10535
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UniProt
- O75792
Antigène
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