Phospholipase C beta 2 anticorps (AA 27-1185)

N° du produit ABIN7600992

Cet anticorps Lapin Polyclonal détecte spécifiquement Phospholipase C beta 2 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour Phospholipase C beta 2 anticorps (AA 27-1185) (ABIN7600992)

Antigène: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholipase C beta 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Phospholipase C beta 2 anticorps

Épitope: AA 27-1185

Fonction: Anti-PLCB2 Antibody Picoband®

Attributs du produit: Anti-PLCB2 Antibody Picoband® (ABIN7600992). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PLCB2 recombinant protein (Position: D27-L1185). Human PLCB2 shares 85.7% and 85.3% amino acid (aa) sequence identity with mouse and rat PLCB2, respectively.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lee, S. B., Rao, A. K., Lee, K.-H., Yang, X., Bae, Y. S., Rhee, S. G. Decreased expression of phospholipase C-b2 isozyme in human platelets with impaired function. Blood 88: 1684-1691, 1996. 2. Li, Z., Jiang, H., Xie, W., Zhang, Z., Smrcka, A. V., Wu, D. Roles of PLC-beta-2 and -beta-3 and PI3K-gamma in chemoattractant-mediated signal transduction. Science 287: 1046-1049, 2000. 3. Mao, G. F., Vaidyula, V. R., Kunapuli, S. P., Rao, A. K. Lineage-specific defect in gene expression in human platelet phospholipase C-beta-2 deficiency. Blood 99: 905-911, 2002.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Phospholipase C beta 2

Antigène: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Autre désignation: PLCB2

Sujet: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

Poids moléculaire: 140 kDa

ID gène: 5330

UniProt: Q00722

Pathways: Signalisation WNT, Thyroid Hormone Synthesis, CXCR4-mediated Signaling Events, G-protein mediated Events, Thromboxane A2 Receptor Signaling