ITGA4 anticorps (AA 41-963)
Aperçu rapide pour ITGA4 anticorps (AA 41-963) (ABIN7601675)
Antigène
Voir toutes ITGA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 41-963
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Fonction
- Anti-Integrin Alpha 4/Itga4 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.
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Attributs du produit
- Anti-Integrin Alpha 4/Itga4 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived mouse Integrin Alpha 4/Itga4 recombinant protein (Position: Y41-D963). Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- ITGA4 (Integrin alpha 4 (ITGA4))
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Autre désignation
- Itga4
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Sujet
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Background: CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
Gene Full Name: integrin alpha 4
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Poids moléculaire
- 150-180 kDa
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ID gène
- 16401
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UniProt
- Q00651
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Pathways
- Integrin Complex
Antigène
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