Mesothelin anticorps (AA 44-497)

N° du produit ABIN7601746

L’anticorps anti-Mesothelin Polyclonal Lapin est utilisé pour la détection de Mesothelin dans des échantillons de Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour Mesothelin anticorps (AA 44-497) (ABIN7601746)

Antigène: Mesothelin (MSLN)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Mesothelin anticorps

Épitope: AA 44-497

Fonction: Anti-Mesothelin/Msln Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Mesothelin/Msln Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Mesothelin/Msln recombinant protein (Position: Q44-K497).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: Msln

Sujet:

Background: Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

Gene Full Name: mesothelin

Poids moléculaire: 69 kDa

ID gène: 56047

UniProt: Q61468

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process