L’anticorps anti-Melanophilin Polyclonal produit chez le Lapin a été validé pour WB, ELISA, IF et ICC. Il convient pour la détection de Melanophilin dans des échantillons provenant de Humain.
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Anti-MLPH Antibody (ABIN7602169). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
Purification
Immunogen affinity purified.
Immunogène
E.coli-derived human Melanophilin/MLPH recombinant protein (Position: E61-L523). Human Melanophilin/MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin/MLPH.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Antigène
Melanophilin (MLPH)
Autre désignation
MLPH
Sujet
Melanophilin is a carrier protein which in humans is encoded by the MLPH gene. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.