Desmoplakin anticorps (AA 69-2195)
Aperçu rapide pour Desmoplakin anticorps (AA 69-2195) (ABIN7602296)
Antigène
Voir toutes Desmoplakin (DSP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 69-2195
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Fonction
- Anti-Desmoplakin/DSP Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Desmoplakin/DSP Antibody (ABIN7602296). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Desmoplakin/DSP recombinant protein (Position: N69-H2195).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Desmoplakin (DSP)
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Autre désignation
- DSP
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Sujet
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Synonyms: Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
Tissue Specificity: Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.
Background: Desmoplakin is a protein in humans that is encoded by the DSP gene. This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 250 kDa
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ID gène
- 1832
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UniProt
- P15924
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Pathways
- Cell-Cell Junction Organization
Antigène
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