WIPF1 anticorps (C-Term)

N° du produit ABIN7602942

Cet anticorps Lapin Polyclonal détecte spécifiquement WIPF1 dans WB et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour WIPF1 anticorps (C-Term) (ABIN7602942)

Antigène: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WIPF1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-WIPF1 anticorps

Épitope: C-Term

Fonction: Anti-WIPF1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-WIPF1 Antibody Picoband® (ABIN7602942). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human WIPF1, which shares 95% amino acid (aa) sequence identity with mouse and rat WIPF1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Al-Mousa, H., Hawwari, A., Al-Ghonaium, A., Al-Saud, B., Al-Dhekri, H., Al-Muhsen, S., Elshorbagi, S., Dasouki, M., El-Baik, L., Alseraihy, A., Ayas, M., Arnaout, R. Hematopoietic stem cell transplantation corrects WIP deficiency. (Letter) J. Allergy Clin. Immun. 139: 1039-1040, 2017. 2. Anton, I. M., de la Fuente, M. A., Sims, T. N., Freeman, S., Ramesh, N., Hartwig, J. H., Dustin, M. L., Geha, R. S. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity 16: 193-204, 2002. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/23/2012.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur WIPF1

Antigène: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Autre désignation: WIPF1

Sujet:

Synonyms: Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF

Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

Background: WAS/WASL-interacting protein (WIP) is a protein that in humans is encoded by the WIPF1 gene. This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.

Poids moléculaire: 56 kDa

ID gène: 7456

UniProt: O43516

Pathways: Signalisation RTK