ATG4A anticorps (C-Term)
Aperçu rapide pour ATG4A anticorps (C-Term) (ABIN7602947)
Antigène
Voir toutes ATG4A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Fonction
- Anti-Atg4A Monoclonal Antibody
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Attributs du produit
- Anti-Atg4A Monoclonal Antibody (ABIN7602947). Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human Atg4A The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue.
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Isotype
- IgG
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Indications d'application
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WB 1:500-1:2000
IHC 1:50-1:200
IP 1:50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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Autre désignation
- ATG4A
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Sujet
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Synonyms: Death domain-containing protein CRADD,Caspase and RIP adapter with death domain,RIP-associated protein with a death domain,CRADD,RAIDD,
Tissue Specificity: Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
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Poids moléculaire
- 45 kDa
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Pathways
- Autophagy
Antigène
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