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ATG4A anticorps (C-Term)

Cet anticorps anti-ATG4A est un anticorps Lapin Monoclonal détectant ATG4A dans WB, IHC et IP. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7602947

Aperçu rapide pour ATG4A anticorps (C-Term) (ABIN7602947)

Antigène

Voir toutes ATG4A Anticorps
ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Reactivité

  • 56
  • 35
  • 29
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 49
  • 4
  • 2
  • 1
Lapin

Clonalité

  • 51
  • 5
Monoclonal

Conjugué

  • 32
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ATG4A est non-conjugé

Application

  • 26
  • 23
  • 14
  • 13
  • 10
  • 8
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone

ACHB-1
  • Épitope

    • 15
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Fonction

    Anti-Atg4A Monoclonal Antibody

    Attributs du produit

    Anti-Atg4A Monoclonal Antibody (ABIN7602947). Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

    Purification

    Affinity-chromatography

    Immunogène

    A synthesized peptide derived from human Atg4A The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue.

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000
    IHC 1:50-1:200
    IP 1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    Concentration

    Lot specific

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • Antigène

    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

    Autre désignation

    ATG4A

    Sujet

    Synonyms: Death domain-containing protein CRADD,Caspase and RIP adapter with death domain,RIP-associated protein with a death domain,CRADD,RAIDD,

    Tissue Specificity: Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.

    Poids moléculaire

    45 kDa

    Pathways

    Autophagy
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