ARID3A anticorps (N-Term)

N° du produit ABIN7603197

Cet anticorps Lapin Polyclonal détecte spécifiquement ARID3A dans WB, IP et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ARID3A anticorps (N-Term) (ABIN7603197)

Antigène: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARID3A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Détail du produit anti-ARID3A anticorps

Épitope: N-Term

Fonction: Anti-ARID3A Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-ARID3A Antibody Picoband® (ABIN7603197). Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ARID3A, which shares 95.8% amino acid (aa) sequence identity with mouse ARID3A.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Alejo-Valle, O., Weigert, K., Bhayadia, R., Ng, M., Issa, H., Beyer, C., Emmrich, S., Schuschel, K., Ihling, C., Sinz, A., Zimmermann, M., Wickenhauser, C., Flasinski, M., Regenyi, E., Labuhn, M., Reinhardt, D., Yaspo, M. L., Heckl, D., Klusmann, J. H. The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. Blood 139: 651-665, 2022. 2. Herrscher, R. F., Kaplan, M. H., Lelsz, D. L., Das, C., Scheuermann, R., Tucker, P. W. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 9: 3067-3082, 1995. 3. Kortschak, R. D., Reimann, H., Zimmer, M., Eyre, H. J., Saint, R., Jenne, D. E. The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome. Genomics 51: 288-292, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ARID3A

Antigène: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Autre désignation: ARID3A

Sujet:

Synonyms: ARID3A, DRIL1, DRIL3, DRX, E2FBP1, AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, B-cell regulator of IgH transcription, Bright, Dead ringer-like protein 1, E2F-binding protein 1

Background: AT-rich interactive domain-containing protein 3A is a protein that in humans is encoded by the ARID3A gene. This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.

Poids moléculaire: 80 kDa

ID gène: 1820

UniProt: Q99856

Pathways: Chromatin Binding