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ISL1 anticorps

Cet anticorps anti-ISL1 est un anticorps Lapin Monoclonal détectant ISL1 dans WB, IHC, IF, IP, ICC et FACS. Adapté pour Humain.
N° du produit ABIN7605323

Aperçu rapide pour ISL1 anticorps (ABIN7605323)

Antigène

Voir toutes ISL1 Anticorps
ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité

  • 79
  • 50
  • 33
  • 8
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 76
  • 11
Lapin

Clonalité

  • 64
  • 23
Monoclonal

Conjugué

  • 44
  • 6
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ISL1 est non-conjugé

Application

  • 60
  • 33
  • 14
  • 13
  • 9
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  • 7
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  • 4
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

AFIA-9
  • Fonction

    Anti-Islet1 Monoclonal Antibody

    Attributs du produit

    Anti-Islet1 Monoclonal Antibody (ABIN7605323). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

    Purification

    Affinity-chromatography

    Immunogène

    A synthesized peptide derived from human Islet1 ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000
    IHC 1:50-1:200
    ICC/IF 1:50-1:200
    IP 1:50
    FC 1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    Concentration

    Lot specific

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • Antigène

    ISL1 (ISL LIM Homeobox 1 (ISL1))

    Autre désignation

    ISL1

    Sujet

    Synonyms: Insulin gene enhancer protein ISL-1,Islet-1,ISL1,

    Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

    Poids moléculaire

    28 kDa

    UniProt

    P61371

    Pathways

    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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