EGLN1 anticorps

N° du produit ABIN7605935

Cet anticorps anti-EGLN1 Monoclonal Lapin (Clone ACEF-5) (ABIN7605935) détecte spécifiquement EGLN1 dans WB et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EGLN1 anticorps (ABIN7605935)

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EGLN1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: ACEF-5

Détail du produit anti-EGLN1 anticorps

Fonction: Anti-PHD2 / prolyl hydroxylase Monoclonal Antibody

Attributs du produit: Anti-PHD2 / prolyl hydroxylase Monoclonal Antibody. Tested in WB, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human PHD2 / prolyl hydroxylase Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000IP 1:20

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EGLN1

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Autre désignation: EGLN1

Sujet: Egl-9 family hypoxia inducible factor 1

Poids moléculaire: 52 kDa

ID gène: 54583

UniProt: Q9GZT9

Pathways: cAMP Metabolic Process, L'effet Warburg