EGLN1 anticorps (C-Term)

N° du produit ABIN1537273

Détail du produit anti-EGLN1 anticorps

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Épitope: AA 396-425, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGLN1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EGLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human EGLN1.

Clone: RB39542

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: EGLN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur EGLN1

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Autre désignation: EGLN1 (EGLN1 Produits)

Synonymes: anticorps EGLN1, anticorps egln2, anticorps phd2, anticorps zgc:92314, anticorps AI503754, anticorps C1orf12, anticorps HIF-PH2, anticorps HPH-2, anticorps Hif-p4h-2, anticorps ORF13, anticorps Phd2, anticorps SM-20, anticorps PHD-2, anticorps PHD2, anticorps ECYT3, anticorps HIFPH2, anticorps HPH2, anticorps SM20, anticorps ZMYND6, anticorps egl nine homolog 1 (C. elegans), anticorps egl-9 family hypoxia inducible factor 1, anticorps egl-9 family hypoxia-inducible factor 1 S homeolog, anticorps egl-9 family hypoxia-inducible factor 1b, anticorps egl-9 family hypoxia-inducible factor 1, anticorps EGLN1, anticorps egln1.S, anticorps egln1b, anticorps Egln1

Sujet: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

Poids moléculaire: 46021

ID gène: 54583

NCBI Accession: NP_071334

UniProt: Q9GZT9

Pathways: cAMP Metabolic Process, L'effet Warburg