Cyclin C anticorps (AA 23-100)

N° du produit ABIN727250

Détail du produit anti-Cyclin C anticorps

Antigène: Cyclin C (CCNC)

Épitope: AA 23-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cyclin C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Cyclin C

Antigène: Cyclin C (CCNC)

Autre désignation: Cyclin C (CCNC Produits)

Synonymes: anticorps CG1C_DROME, anticorps CG7281, anticorps CYCC, anticorps Cln3, anticorps Cyc-C, anticorps DmcycC, anticorps Dmel\\CG7281, anticorps SRB11, anticorps cycC, anticorps cyclinC, anticorps dTRAP33, anticorps fj11d06, anticorps wu:fj11d06, anticorps zgc:73078, anticorps Cyclin-C, anticorps CycC, anticorps AI451004, anticorps AU020987, anticorps CG1C, anticorps Cyclin C, anticorps cyclin C, anticorps cyclin C L homeolog, anticorps cyclin-C, anticorps CycC, anticorps ccnc, anticorps CCNC, anticorps Ccnc, anticorps ccnc.L, anticorps LOC5577815

Sujet:

Synonyms: CycC, Cyclin-C, SRB11 homolog, hSRB11, CCNC

Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

ID gène: 892

UniProt: P24863

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha