CD44 anticorps (Biotin)
Aperçu rapide pour CD44 anticorps (Biotin) (ABIN7608117)
Antigène
Voir toutes CD44 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Biotinylated Anti-CD44 antibody(DMC269), IgG1 Chimeric mAb
-
Purification
- Purified from cell culture supernatant by affinity chromatography
-
Isotype
- IgG1
-
-
-
-
Indications d'application
- Flow Cyt 1:100
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Date de péremption
- 12 months
-
-
- CD44
-
Autre désignation
- CD44
-
Sujet
- The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
-
UniProt
- P16070
-
Pathways
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
Antigène
-