Angiopoietin 1 anticorps (AA 276-375)

N° du produit ABIN728323

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiopoietin 1 dans WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 5+ publications.

Aperçu rapide pour Angiopoietin 1 anticorps (AA 276-375) (ABIN728323)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: AA 276-375

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse Angiopoietin 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Angiopoietin 1 (ABIN728323)

Xiang, Hu, Shen, Liu, Hua, Zan, Zu, Cui, Ye: "Bone marrow mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke in type 2 diabetic rats." dans: Neuroscience letters, Vol. 644, pp. 62-66, (2017) (PubMed).

Zhou, Deng, Hu, Wang, Chen, Cui, Cao, Song: "Ultrasound combined with targeted cationic microbubble-mediated angiogenesis gene transfection improves ischemic heart function." dans: Experimental and therapeutic medicine, Vol. 13, Issue 5, pp. 2293-2303, (2017) (PubMed).

He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." dans: Cancer letters, Vol. 368, Issue 1, pp. 115-25, (2015) (PubMed).

Zhao, Hu, Xiang, Gu, Jin, Hua, Zhang, Liu, Zan, Zhang, Zu, Yang, Shi, Zhu, Xu, Cui, Ye: "Intranasal administration of human umbilical cord mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke." dans: Brain research, (2015) (PubMed).

Lv, Fan, Su: "Is a swine model of arteriovenous malformation suitable for human extracranial arteriovenous malformation? A preliminary study." dans: Cardiovascular and interventional radiology, Vol. 36, Issue 5, pp. 1364-70, (2013) (PubMed).

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin 1

Sujet:

Synonyms: AGP 1, AGP1, AGPT, ANG 1, ANG1, Angiopoietin1, Angiogenin, ANGPT 1, ANGPT1, ANGPT-1, Angiopoietin-1, Angiopoietin 1, ANG-1, angiopoietin-1 isoform 1 precursor, ANGP1_HUMAN.

Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].

ID gène: 11600

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process