YWHAE anticorps

N° du produit ABIN7649011

Cet anticorps Souris Monoclonal détecte spécifiquement YWHAE dans WB, IHC et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour YWHAE anticorps (ABIN7649011)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YWHAE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CPTC-YWHAE-1

Détail du produit anti-YWHAE anticorps

Fonction: 14-3-3E / Tryptophan 5-Monooxygenase(CPTC-YWHAE-1)

Attributs du produit: 14-3-3E is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human full-length YWHAE protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: HEK-293 or A-431 cell lines.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur YWHAE

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: 14-3-3E

Sujet:

Synonyms: YWHAE, Tyrosine 3-Monooxygenase Activation Protein Epsilon, Tryptophan 5-Monooxygenase Activation Protein Epsilon, epididymis luminal protein 2, Mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1

Gene Symbol: YWHAE

Poids moléculaire: 29.4 kDa

ID gène: 7531

UniProt: P62268

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase