CTNND1 anticorps (CF®740)
Aperçu rapide pour CTNND1 anticorps (CF®740) (ABIN7650595)
Antigène
Voir toutes CTNND1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Catenin, delta-1 (CTNND1) (pTyr96) (25a), CF740 conjugate
-
Attributs du produit
- Delta 1 catenin, also known as p120 catenin, is a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other cadherins. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogène
- Mouse p120 Catenin (pY96)
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
-
Commentaires
-
Positive Control: Carcinoma
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.1 mg/mL
-
Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Protect from light
-
Stock
- 4 °C
-
Stockage commentaire
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
Date de péremption
- 24 months
-
-
- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
-
Autre désignation
- Catenin, Delta-1
-
Sujet
-
Synonyms: Delta 1 cadherin, Catenin delta-1, Cadherin-associated Src substrate (CAS), Catenin (cadherin associated protein) delta 1, CTNND1, p120 catenin
Gene Symbol: CTNND1
Tissue Expression: Epithelial cells
-
Poids moléculaire
- 120 kDa
-
ID gène
- 1500
-
Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Antigène
-