Recombinant IGF1 anticorps (Biotin)

N° du produit ABIN7655347

Cet anticorps Lapin Monoclonal détecte spécifiquement IGF1 dans FACS. Il présente une réactivité envers Humain, Souris, Rat et Lapin.

Aperçu rapide pour Recombinant IGF1 anticorps (Biotin) (ABIN7655347)

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: IGF1-2872R

Détail du produit anti-IGF1 anticorps (Biotin)

Fonction: Insulin-like Growth Factor-1 (IGF-1) (IGF1/2872R), Biotin conjugate

Attributs du produit: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human IGF-1 protein

Isotype: IgG

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. ELISA For coating, order Ab without BSA. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: Pancreas or brain. Breast, Thyroid or Colon Cancers, IGF-1 recombinant protein

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur IGF1

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: Insulin-like Growth Factor-1

Sujet:

Synonyms: Insulin-like Growth Factor IA (IGF-IA), Insulin-like Growth Factor IB (IGF-IB), Mechano Growth Factor (MGF), Somatomedin-C

Gene Symbol: IGF1

Poids moléculaire: ~7.6 kDa

ID gène: 3479

UniProt: P05019

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation