FcRn anticorps (AA 24-215) (CF®488A)

N° du produit ABIN7657760

L’anticorps Souris Monoclonal anti-FcRn a été validé pour IHC et IHC (fp). Il convient pour détecter FcRn dans des échantillons de Humain.

Aperçu rapide pour FcRn anticorps (AA 24-215) (CF®488A) (ABIN7657760)

Antigène: FcRn (neonatal Fc Receptor (FcRn))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FcRn est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: FCGRT-2932

Détail du produit anti-FcRn anticorps (CF®488A)

Épitope: AA 24-215

Fonction: FCGRT / FcRn (IgG Transporter)(FCGRT/2932), CF488A conjugate

Attributs du produit: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment of human FCGRT protein (around aa 24-215)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: THP1 or HepG2 cells. Cerebellum or Testis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur FcRn

Antigène: FcRn (neonatal Fc Receptor (FcRn))

Autre désignation: FCGRT

Sujet:

Synonyms: Fc fragment of IgG, receptor transporter, alpha, FCGRT, FCRN, alpha chain, IgG Fc fragment receptor transporter alpha chain, IgG Gc receptor, IgG receptor FcRn large subunit p51, Immunoglobulin receptor, intestinal, heavy chain, Neonatal Fc receptor

Gene Symbol: FCGRT

Poids moléculaire: 46 kDa

ID gène: 2217

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process