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Melanoma gp100 anticorps (CF®568)

Cet anticorps Lapin Polyclonal détecte spécifiquement Melanoma gp100 dans IHC, WB et IHC (fp). Il présente une réactivité envers Humain.
N° du produit ABIN7658893

Aperçu rapide pour Melanoma gp100 anticorps (CF®568) (ABIN7658893)

Antigène

Voir toutes Melanoma gp100 (PMEL) Anticorps
Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reactivité

  • 112
  • 13
  • 8
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 60
  • 50
  • 2
  • 1
Lapin

Clonalité

  • 63
  • 48
  • 2
Polyclonal

Conjugué

  • 56
  • 9
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Melanoma gp100 est conjugé à/à la CF®568

Application

  • 60
  • 59
  • 43
  • 42
  • 26
  • 19
  • 14
  • 7
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • Fonction

    gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(N/A), CF568 conjugate

    Attributs du produit

    Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant full-length human SILV protein

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Positive Control: SK-MEL-28 cells. Melanoma.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

    Autre désignation

    gp100

    Sujet

    Synonyms: 95 kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog

    Gene Symbol: SILV

    Tissue Expression: Melanocytes

    Poids moléculaire

    90-100 kDa

    ID gène

    6490

    UniProt

    P40967
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