Melanoma gp100 anticorps (CF®568)
Aperçu rapide pour Melanoma gp100 anticorps (CF®568) (ABIN7658893)
Antigène
Voir toutes Melanoma gp100 (PMEL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(N/A), CF568 conjugate
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Attributs du produit
- Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant full-length human SILV protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: SK-MEL-28 cells. Melanoma.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Autre désignation
- gp100
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Sujet
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Synonyms: 95 kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
Gene Symbol: SILV
Tissue Expression: Melanocytes
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Poids moléculaire
- 90-100 kDa
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ID gène
- 6490
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UniProt
- P40967
Antigène
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