PMEPA1 anticorps (CF®405S)

N° du produit ABIN7659298

Cet anticorps Souris Monoclonal détecte spécifiquement PMEPA1 dans IHC et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour PMEPA1 anticorps (CF®405S) (ABIN7659298)

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PMEPA1 est conjugé à/à la CF®405S

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: PMEPA1-2696

Détail du produit anti-PMEPA1 anticorps (CF®405S)

Fonction: PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2696), CF405S conjugate

Attributs du produit: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human PMEPA1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Human prostate, breast or renal cell carcinoma tissue (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur PMEPA1

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Autre désignation: PMEPA1

Sujet:

Synonyms: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

Gene Symbol: PMEPA1

Tissue Expression: Kidney|Ovary|Prostate

Poids moléculaire: 32 kDa

ID gène: 56937

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway