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PMEPA1 anticorps (CF®640R)

L’anticorps Souris Monoclonal anti-PMEPA1 a été validé pour IHC et IHC (fp). Il convient pour détecter PMEPA1 dans des échantillons de Humain.
N° du produit ABIN7659302

Aperçu rapide pour PMEPA1 anticorps (CF®640R) (ABIN7659302)

Antigène

Voir toutes PMEPA1 Anticorps
PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivité

  • 36
  • 3
  • 2
Humain

Hôte

  • 24
  • 12
Souris

Clonalité

  • 25
  • 11
Monoclonal

Conjugué

  • 19
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp PMEPA1 est conjugé à/à la CF®640R

Application

  • 26
  • 17
  • 13
  • 11
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

PMEPA1-2697
  • Fonction

    PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2697), CF640R conjugate

    Attributs du produit

    PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant full-length human PMEPA1 protein

    Isotype

    IgG, kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Positive Control: SKBR-3 cells. Prostate, Breast or Renal Cell Carcinoma.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

    Autre désignation

    PMEPA1

    Sujet

    Synonyms: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

    Gene Symbol: PMEPA1

    Tissue Expression: Kidney|Ovary|Prostate

    Poids moléculaire

    32 kDa

    ID gène

    56937

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway
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