Recombinant TLE1 anticorps (AA 175-338)

N° du produit ABIN7660999

Cet anticorps Lapin Monoclonal détecte spécifiquement TLE1 dans IHC et IHC (fp). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant TLE1 anticorps (AA 175-338) (ABIN7660999)

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: TLE1-2946R

Détail du produit anti-TLE1 anticorps

Épitope: AA 175-338

Fonction: TLE1 (Synovial Sarcoma Marker) (TLE1/2946R)

Attributs du produit: Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human TLE1 fragment (aa 175-338)

Isotype: IgG

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1

Sujet:

Synonyms: Enhancer of split groucho 1 (ESG1), Enhancer of split groucho-like protein 1, GRG1, TLE1, Transducin like enhancer of split 1, Transducin-like enhancer protein 1

Gene Symbol: TLE1

Poids moléculaire: 83 kDa

ID gène: 7088

UniProt: Q04724

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome