CD19 anticorps

N° du produit ABIN7669991

Cet anticorps anti-CD19 Monoclonal Lapin (Clone HD37) (ABIN7669991) détecte spécifiquement CD19 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD19 anticorps (ABIN7669991)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD19 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: HD37

Détail du produit anti-CD19 anticorps

Fonction: Purified Anti-Human CD19 Antibody[HD37]

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze / thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet: CVID,B-lymphocyteantigenCD,B-lymphocyte antigen CD,T-cellsurfaceantigenLeu,Differentiation antigen CD,T-cell surface antigen Leu,B-lymphocytesurfaceantigenB,B-lymphocyte surface antigen B,B4,CVID3,CD19,B-lymphocyteantigenCD19,B-lymphocytesurfaceantigenB4,T-cellsurfaceantigenLeu-12,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12,B4,CVID3,CD19,CD19 Molecule,CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.

UniProt: P15391

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway