CD14 anticorps

N° du produit ABIN7670148

Cet anticorps Souris Monoclonal détecte spécifiquement CD14 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD14 anticorps (ABIN7670148)

Antigène: CD14

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: M5E2

Détail du produit anti-CD14 anticorps

Fonction: AF/LE Purified Anti-Human CD14 Antibody[M5E2]

niveau d'endotoxine: Low Endotoxin

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Agent conservateur: Azide free

Conseil sur la manipulation: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Date de péremption: 12 months

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: Monocyte differentiation antigen CD,CD14,soluble,CD14 antigen,CD14 Molecule,monocyte differentiation antigen CD14,Myeloid cell-specific leucine-rich glycoprotein,LPS R,CD 14,CD_antigen=CD14,LPS-R,membrane-bound form,Mo2,Monocyte differentiation antigen CD14 urinary form,Myeloid cell specific leucine rich glycoprotein,The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

UniProt: P08571

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades