CD86 anticorps
Aperçu rapide pour CD86 anticorps (ABIN7670563)
Antigène
Voir toutes CD86 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- B7-2/CD86 Polyclonal Antibody(Capture/Detector)
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Purification
- Antigen Affinity Purification
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Immunogène
- Recombinant Rat B7-2/CD86 protein expressed by Mammalian
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Isotype
- IgG
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Indications d'application
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Sterile PBS , pH 7.4
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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Date de péremption
- 12 months
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- CD86
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Autre désignation
- B7-2/CD86
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Sujet
- SCD86,This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
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UniProt
- O35531
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Antigène
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