Frataxin anticorps

N° du produit ABIN7670612

Cet anticorps Lapin Polyclonal détecte spécifiquement Frataxin dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Frataxin anticorps (ABIN7670612)

Antigène: Frataxin (FXN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: ELISA

Détail du produit anti-Frataxin anticorps

Fonction: Frataxin/FXN Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human Frataxin/FXN protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: Frataxin/FXN

Sujet: CyaY,d-FXN,FA,FARR,Frataxin mature form,Frataxin(81-210),FRDA,FRDA,Friedreich ataxia protein,Fxn,i-FXN,m56-FXN,m78-FXN,m81-FXN,MGC57199,X25,FXN,also named as FRDA,X25,m81-FXN,d-FXN,m78-FXN and i-FXN,belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. FXN is expressed in the cytoplasm as a 210 amino acid (AA) precursor protein (pFXN, 23?KDa) that is translocated into mitochondria where it is processed by two consecutive steps into iFXN (FXN 42-210, 19?KDa) and finally mFXN (81-210, 14.2?KDa),which is functional.

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size