SNCA anticorps

N° du produit ABIN7670750

Cet anticorps Rat Monoclonal détecte spécifiquement SNCA dans ELISA (Capture). Il présente une réactivité envers Humain.

Aperçu rapide pour SNCA anticorps (ABIN7670750)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: ELISA (Capture)

Clone: 6B2

Détail du produit anti-SNCA anticorps

Fonction: alpha-Synuclein/SNCA Monoclonal Antibody(Capture)

Purification: Protein A/G Purification

Immunogène: Recombinant Human alpha-Synuclein/SNCA protein expressed by E.coli

Isotype: IgM

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: alpha-Synuclein/SNCA

Sujet: SNC-A,aSYN,PD1,NACP,PARK1,PARK4,Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity