Acetyl-CoA Carboxylase alpha anticorps (AA 2223-2346)

N° du produit ABIN7672612

Cet anticorps anti-Acetyl-CoA Carboxylase alpha est un anticorps Souris Monoclonal détectant Acetyl-CoA Carboxylase alpha dans WB, IHC et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour Acetyl-CoA Carboxylase alpha anticorps (AA 2223-2346) (ABIN7672612)

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 9D2

Détail du produit anti-Acetyl-CoA Carboxylase alpha anticorps

Épitope: AA 2223-2346

Fonction: ACC1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 2223-2346aa

Immunogen: acetyl-Coenzyme A carboxylase alpha

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:2000-1:10000, IHC: 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Acetyl-CoA Carboxylase alpha

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Autre désignation: ACC1

Sujet:

Synonyms: Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA

Background: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

Poids moléculaire: 270 kDa

ID gène: 31

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, L'effet Warburg