Beclin 1 anticorps

N° du produit ABIN7672911

L’anticorps Souris Monoclonal anti-Beclin 1 a été validé pour WB, ELISA et IHC. Il convient pour détecter Beclin 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Beclin 1 anticorps (ABIN7672911)

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Beclin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 1G5

Détail du produit anti-Beclin 1 anticorps

Fonction: BECN1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 141-450

Immunogen: beclin 1, autophagy related

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500 - 1:5000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Beclin 1

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Autre désignation: BECN1

Sujet:

Synonyms: Beclin-1|Coiled-coil myosin-like BCL2-interacting protein|Protein GT197|Beclin-1-C 35 kDa|Beclin-1-C 37 kDa|BECN1|GT197

Background: Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

Poids moléculaire: 60 kDa

ID gène: 8678

UniProt: Q14457

Pathways: Autophagy