Mesothelin anticorps

N° du produit ABIN7673469

L’anticorps anti-Mesothelin Polyclonal Lapin est utilisé pour la détection de Mesothelin dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour Mesothelin anticorps (ABIN7673469)

Antigène: Mesothelin (MSLN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Mesothelin anticorps

Fonction: MSLN antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Mesothelin

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: MSLN

Sujet:

Synonyms: Mesothelin|CAK1 antigen|Pre-pro-megakaryocyte-potentiating factor|Megakaryocyte-potentiating factor (MPF)|Mesothelin, cleaved form|MSLN|MPF

Background: Mesothelin (MSLN) is a 40 kDa GPI-anchored surface glycoprotein that is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71 kDa precursor protein that is processed to a 40 kDa membrane-bound protein termed mesothelin and a 31 kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell.

Poids moléculaire: 70 kDa, 40 kDa

ID gène: 10232

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process