CD80 anticorps (PerCP-Cy5.5)

N° du produit ABIN7674334

Cet anticorps anti-CD80 est un anticorps Hamster arménien Monoclonal détectant CD80 dans FACS. Adapté pour Souris.

Aperçu rapide pour CD80 anticorps (PerCP-Cy5.5) (ABIN7674334)

Antigène: CD80

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est conjugé à/à la PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: 16-10A1

Détail du produit anti-CD80 anticorps (PerCP-Cy5.5)

Fonction: PerCP-Cy5.5 Anti-Mouse CD80 Antibody

Purification: 0

Pureté: 0

Isotype: IgG

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Sujet:

Synonyms: Activation B7-1 antigen|B7|Cd80|T-lymphocyte activation antigen CD80

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Poids moléculaire: 0

ID gène: 12519

UniProt: Q00609

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints