CSF1R anticorps (FineTest®700)

N° du produit ABIN7675085

Cet anticorps anti-CSF1R est un anticorps Rat Monoclonal détectant CSF1R dans FACS. Adapté pour Souris.

Aperçu rapide pour CSF1R anticorps (FineTest®700) (ABIN7675085)

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CSF1R est conjugé à/à la FineTest®700

Application: Flow Cytometry (FACS)

Clone: AFS98

Détail du produit anti-CSF1R anticorps (FineTest®700)

Fonction: FineTest®700 Anti-Mouse CD115/CSF-1R Antibody

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CD115

Sujet:

Synonyms: CD115|CSF-1 receptor (EC:2.7.10.1)|CSF-1-R|CSF-1R|Csf1r|Csfmr|Fms|M-CSF-R|Macrophage colony-stimulating factor 1 receptor|Proto-oncogene c-Fms

Background: CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.

Poids moléculaire: 0

ID gène: 12978

UniProt: P09581

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization