Frataxin anticorps (AA 20-210)

N° du produit ABIN7825383

Cet anticorps Lapin Polyclonal détecte spécifiquement Frataxin dans WB, ELISA, IHC et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Frataxin anticorps (AA 20-210) (ABIN7825383)

Antigène: Frataxin (FXN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-Frataxin anticorps

Épitope: AA 20-210

Fonction: Anti-FXN Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human FXN shares 79%,71.4% amino acid (aa) sequence identity with mouse,rat FXN,respectively.

Attributs du produit: Anti-FXN Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FXN recombinant protein (Position: Q20-A210). Human FXN shares 79% and 71.4% amino acid (aa) sequence identity with mouse and rat FXN, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: FXN

Sujet:

Background: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Gene Full Name: frataxin

Poids moléculaire: 14 kDa

ID gène: 2395

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size