Recombinant Aurora Kinase B anticorps

N° du produit ABIN7828032

Cet anticorps anti-Aurora Kinase B Monoclonal Lapin (Clone A136) (ABIN7828032) détecte spécifiquement Aurora Kinase B dans IHC, WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant Aurora Kinase B anticorps (ABIN7828032)

Antigène: Aurora Kinase B (AURKB)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Clone: A136

Détail du produit anti-Aurora Kinase B anticorps

Fonction: Recombinant Aurora B Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Aurora B fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: Aurora B

Sujet: IPL,ARK,AIK,AIRK,PPP1R,STK,AIM,AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,PPP1R48,STK12,STK5,aurkb-sv1,aurkb-sv2,AURKB,Aurora B,AIRK2,STK1,Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 39 kDa

Observed MW: 39 kDa

UniProt: Q96GD4

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades