Recombinant beta-2 Microglobulin anticorps

N° du produit ABIN7828042

Cet anticorps Lapin Monoclonal détecte spécifiquement beta-2 Microglobulin dans WB et IHC. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Recombinant beta-2 Microglobulin anticorps (ABIN7828042)

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp beta-2 Microglobulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A561

Détail du produit anti-beta-2 Microglobulin anticorps

Fonction: Recombinant beta-2-Microglobulin Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human beta-2-Microglobulin fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur beta-2 Microglobulin

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Autre désignation: beta-2-Microglobulin

Sujet: IMD,Beta-2-microglobulin form pI,CDABP,B2M,IMD43,B2MG,Beta 2 microglobin,Beta 2 microglobulin,Beta 2 microglobulin precursor,Beta chain of mhc class 1 proteins,Beta chain of MHC class I molecules,Beta-2-Microglobulin,Beta-2-microglobulin form pI 5.3,β2M,β2-Microglobulin,CDABP0092,HDCMA22P,β2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system. As an integral component of the MHC class I complex, β2-microglobulin plays a critically important role in immune system function. It has important relevance to cancer biology research, for example, research studies have shown that nearly one-third of diffuse large B cell lymphomas contain mutations that inactivate β2-microglobulin gene function, thereby allowing tumor cells to escape immune detection. In addition, β2-microglobulin has been identified as an amyloid preprotein with collagen-binding affinity, its accumulation in osteoarthritic lesions of long-term dialysis patients is reportedly a contributing factor to the condition known as amyloid osteoarthropathy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 14 kDa

Observed MW: 14 kDa

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process