Recombinant CD33 anticorps

N° du produit ABIN7828081

Cet anticorps Lapin Monoclonal détecte spécifiquement CD33 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD33 anticorps (ABIN7828081)

Antigène: CD33

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD33 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: A170

Détail du produit anti-CD33 anticorps

Fonction: Recombinant CD33 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human CD33 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: IHC 1:200-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD33

Antigène: CD33

Autre désignation: CD33

Sujet: CD33,SIGLEC-3,SIGLEC3,p67,CD33 Molecule,gp67,Myeloid cell surface antigen CD33,Sialic acid-binding Ig-like lectin 3,Siglec-3,CD33 Molecule,p67,SIGLEC3,Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK. These phosphorylations provide docking sites for the recruitment and activation of protein-tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. In turn, these phosphatases regulate downstream pathways through dephosphorylation of signaling molecules. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P20138