Recombinant CD3G anticorps

N° du produit ABIN7828083

Cet anticorps anti-CD3G Monoclonal Lapin (Clone A172) (ABIN7828083) détecte spécifiquement CD3G dans WB, IHC, IP et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD3G anticorps (ABIN7828083)

Antigène: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3G est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: A172

Détail du produit anti-CD3G anticorps

Fonction: Recombinant CD3G Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human CD3G fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:500-1:2000,IF 1:50,IP 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD3G

Antigène: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Autre désignation: CD3G

Sujet: T3G,CD3G,T3,CD_antigen: CD3g,CD3g molecule,CD3-GAMMA,IMD17,T-cell receptor T3 gamma chain,T-cell surface glycoprotein CD3 gamma chain,Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 20 kDa

Observed MW: 18-28 kDa The actual band is not consistent with the expectation.

UniProt: P09693

Pathways: TCR Signaling, CXCR4-mediated Signaling Events