Recombinant CENPA anticorps

N° du produit ABIN7828101

Cet anticorps anti-CENPA Monoclonal Lapin (Clone A184) (ABIN7828101) détecte spécifiquement CENPA dans WB, IF, IHC et FACS. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Recombinant CENPA anticorps (ABIN7828101)

Antigène: CENPA (Centromere Protein A (CENPA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CENPA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A184

Détail du produit anti-CENPA anticorps

Fonction: Recombinant CENP-A Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human CENP-A fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:100-1:1000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CENPA

Antigène: CENPA (Centromere Protein A (CENPA))

Autre désignation: CENP-A

Sujet: CenH,CENPA,CENP-A,CenH3,Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore .The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3.May serve as an epigenetic mark that propagates centromere identity through replication and cell division.Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 16 kDa

Observed MW: 18 kDa The actual band is not consistent with the expectation.

UniProt: P49450

Pathways: Chromatin Binding, Maintenance of Protein Location