Recombinant Clusterin anticorps

N° du produit ABIN7828120

Cet anticorps Lapin Monoclonal détecte spécifiquement Clusterin dans WB. Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour Recombinant Clusterin anticorps (ABIN7828120)

Antigène: Clusterin (CLU)

Type d'anticorp: Recombinant Antibody

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Clusterin est non-conjugé

Application: Western Blotting (WB)

Clone: A616

Détail du produit anti-Clusterin anticorps

Fonction: Recombinant Clusterin beta Chain Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Clusterin beta Chain fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Clusterin

Antigène: Clusterin (CLU)

Autre désignation: Clusterin beta Chain

Sujet: KUB,AAG,Ku70-binding protein,Sulfated glycoprotein,Complement-associated protein SP,Testosterone-repressed prostate message,NA1/NA,SGP,CLU,AAG4,APO-J,APOJ,CLI,CLU1,CLU2,KUB1,NA1/NA2,SGP-2,SGP2,SP-40,TRPM-2,TRPM2,clusterin,CLUS,Aging-associated gene 4 protein,Apolipoprotein J,Complement cytolysis inhibitor,Complement-associated protein SP-40,Ku70-binding protein 1,Sulfated glycoprotein2,Testosterone-repressed prostate message 2,Complement cytolysis inhibitor a chain,Clusterin alpha chain,Complement cytolysis inhibitor b chain,APOJ CLI,Sulfated glycoprotein 2,Clusterin (CLU) also named as apolipoprotein J, is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress-induced proteins to prevent their precipitation. Research studies show that clusterin plays a protective role in Alzheimer's disease by sequestering amyloid β (1-40) peptides to form long-lived, stable complexes, which prevents amyloid fibril formation.In addition to the secreted protein, several intracellular isoforms are localized to the nucleus, mitochondria, cytoplasm and ER. The subcellular distribution of these multiple isoforms leads to the diversity of clusterin functions. Additional studies report that clusterin is involved in membrane recycling, cell adhesion, cell proliferation, apoptosis, and tumor survival. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 52 kDa

Observed MW: 35 kDa The actual band is not consistent with the expectation.

UniProt: P10909

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling