Recombinant Cyclin D1 anticorps (pThr286)

N° du produit ABIN7828139

L’anticorps anti-Cyclin D1 Monoclonal Lapin est utilisé pour la détection de Cyclin D1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et FACS.

Aperçu rapide pour Recombinant Cyclin D1 anticorps (pThr286) (ABIN7828139)

Antigène: Cyclin D1 (CCND1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin D1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A202

Détail du produit anti-Cyclin D1 anticorps

Épitope: pThr286

Fonction: Recombinant Phospho-Cyclin D1 (Thr286) Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Phospho-Cyclin D1 (Thr286) fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:50-1:100,FCM 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Cyclin D1

Antigène: Cyclin D1 (CCND1)

Autre désignation: Cyclin D1

Sujet: Cyl,PRAD,U21B,CCND,B cell leukemia,G1/S specific cyclin D,Cyclin D,BCL,BCL1,D11S287E,PRAD1,U21B31,CCND1,Cyclin D1,B cell leukemia 1,BCL 1,Cd1,Cyl 1,G1/S specific cyclin D1,BCL1,D11S287E,PRAD1,U21B31,CCND1,Cyclin D1,cyclin D1,Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 34 kDa

Observed MW: 34 kDa

UniProt: P24385

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, ER-Nucleus Signaling