Recombinant HSD17B1 anticorps

N° du produit ABIN7828297

Cet anticorps Lapin Monoclonal détecte spécifiquement HSD17B1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant HSD17B1 anticorps (ABIN7828297)

Antigène: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HSD17B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A558

Détail du produit anti-HSD17B1 anticorps

Fonction: Recombinant HSD17B1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human HSD17B1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:5000-1:20000,IHC 1:1000-1:5000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur HSD17B1

Antigène: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Autre désignation: HSD17B1

Sujet: HSD,EDHB,HSD17B,SDR28C,HSD17B1,17-beta-HSD,20-alpha-HSD,E2DH,EDH17B2,EDHB17,HSD17,SDR28C1,E17KSR,EDH17B1,17 beta HSD 1,17 beta hydroxysteroid dehydrogenase type 1,17-beta-HSD 1,17-beta-hydroxysteroid dehydrogenase type 1,20 alpha-hydroxysteroid dehydrogenase,DHB1,Estradiol 17 beta dehydrogenase 1,Estradiol 17-beta-dehydrogenase 1,Hydroxysteroid (17 beta) dehydrogenase 1,member 1,MGC13814,Placental 17 beta hydroxysteroid dehydrogenase,Placental 17-beta-hydroxysteroid dehydrogenase,Short chain dehydrogenase/reductase family 28CE,HSD17B1 is a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. HSD17B1 catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. HSD17B1 is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 35 kDa

Observed MW: 35 kDa

UniProt: P14061

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis