Recombinant CD25 anticorps
Aperçu rapide pour Recombinant CD25 anticorps (ABIN7828325)
Antigène
Voir toutes CD25 (IL2RA) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Recombinant CD25 Monoclonal Antibody
-
Purification
- Protein A purified
-
Immunogène
- Recombinant human CD25 fragment
-
Isotype
- IgG, kappa
-
-
-
-
Indications d'application
- IF 1:50,FCM 1:50-1:100
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
Date de péremption
- 12 months
-
-
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
-
Autre désignation
- CD25
-
Sujet
- IMD;IDDM;IL2RA;CD25;IDDM10;IL2R;IMD41;TCGFR;p55;IL-2 receptor subunit alpha;IL-2R subunit alpha;IL2-RA;IL-2-RA;IL-2Rα;Interleukin-2 receptor subunit alpha;TAC antigen;Tac;p55;IL-2Rαalpha chain;CD25 antigen;IL 2 receptor alpha subunit;IL2 RA;Interleukin 2 receptor;Interleukin 2 receptor alpha;Interleukin 2 receptor alpha chain;t-cell growth factor receptor,The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
UniProt
- P01589
-
Pathways
- Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation
Antigène
-