Recombinant PLAT anticorps

N° du produit ABIN7828462

Cet anticorps Lapin Monoclonal détecte spécifiquement PLAT dans WB et IHC. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Recombinant PLAT anticorps (ABIN7828462)

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A725

Détail du produit anti-PLAT anticorps

Fonction: Recombinant Tissue Plasminogen Activator Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PLAT

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Autre désignation: Tissue Plasminogen Activator

Sujet: PLAT,T-PA,TPA,Tissue plasminogen activator,t-plasminogen activator,Alteplase,DKFZp686I03148,Plasminogen activator tissue,Plasminogen activator tissue type,Reteplase,t PA,T Plasminogen Activator,Tissue plasminogen activator (t PA),Tissue type plasminogen activator,Tissue-type plasminogen activator chain B,TPA1,Plasminogen activator, tissue (PLAT, synonyms: TPA, T-PA) is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein (33 kDa and 32 kDa). PLAT enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. tPA has 4 isoforms produced by alternative splicing with the MW of 63 kDa, 33 kDa, 57 kDa and 44 kDa. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 63 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P00750

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome