Recombinant PRMT5 anticorps

N° du produit ABIN7828493

L’anticorps anti-PRMT5 Monoclonal Lapin est utilisé pour la détection de PRMT5 dans des échantillons de Humain. Il a été validé pour WB, IHC et IP.

Aperçu rapide pour Recombinant PRMT5 anticorps (ABIN7828493)

Antigène: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PRMT5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: A338

Détail du produit anti-PRMT5 anticorps

Fonction: Recombinant PRMT5 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human PRMT5 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:2000-1:10000,IHC 1:50-1:100,IP 1:25-1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PRMT5

Antigène: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Autre désignation: PRMT5

Sujet: IBP,JBP,SKB,PRMT,HRMT1L,HRMT1L5,IBP72,JBP1,SKB1,SKB1Hs,PRMT5,72 kDa ICln binding protein,72 kDa ICln-binding protein,ANM5,Histone synthetic lethal 7,Histone-arginine N-methyltransferase PRMT5,HMT1 hnRNP methyltransferase like 5,homolog of,Jak-binding protein 1,JBP 1,PRMT 5,Protein arginine methyltransferase 5,Protein arginine N methyltransferase 5,Protein arginine N methyltransferase 5 N terminally processed,Protein arginine N-methyltransferase 5,S. cerevisiae,S. POMBE,S. POMBE HOMOLOG OF,SHK1 KINASE BINDING PROTEIN 1,Shk1 kinase binding protein 1 homolog,Shk1 kinase/binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB 1,SKB1 homolog,SKB1: SKB1 homolog (S. pombe),Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 73 kDa

Observed MW: 70 kDa The actual band is not consistent with the expectation.

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development