Recombinant DIABLO anticorps

N° du produit ABIN7828549

Cet anticorps Lapin Monoclonal détecte spécifiquement DIABLO dans WB, IHC, IF, IP et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant DIABLO anticorps (ABIN7828549)

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DIABLO est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: A361

Détail du produit anti-DIABLO anticorps

Fonction: Recombinant Smac/Diablo Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Smac/Diablo fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:50-1:100,IF 1:500-1:1000,FCM 1:50-1:100,IP 1:25-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur DIABLO

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Autre désignation: Smac/Diablo

Sujet: DFNA,DIABLO,DFNA64,SMAC,0610041G12Rik,DBLOH,DBOH,Diablo homolog,Diablo homolog (Drosophila),Diablo homolog mitochondrial,Diablo IAP binding mitochondrial protein,Diablo like protein,DIABLO S,Direct IAP binding protein with low pI,Direct IAP-binding protein with low pI,FLJ10537,FLJ25049,mitochondrial,Mitochondrial Smac protein,Second mitochondria derived activator of caspase,Second mitochondria-derived activator of caspase,SMAC 3,Smac protein,SMAC3,Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 27 kDa

Observed MW: 21 kDa The actual band is not consistent with the expectation.

UniProt: Q9NR28

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity