PSME4 anticorps (AA 840-1140)

N° du produit ABIN7833480

Cet anticorps Lapin Polyclonal détecte spécifiquement PSME4 dans WB. Il présente une réactivité avec des échantillons de Arabidopsis thaliana.

Aperçu rapide pour PSME4 anticorps (AA 840-1140) (ABIN7833480)

Antigène: PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))

Reactivité: Arabidopsis thaliana

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSME4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSME4 anticorps

Épitope: AA 840-1140

Fonction: Anti-PA200 | Proteasome activator PA200

Réactivité croisée (Details): Arabidopsis thaliana
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Purification: Serum

Immunogène: PA200 antibodies were generated against a partial fragment encompassing residues 840-1140 Arabidopsis thaliana protein sequence UniProt:F4JC97-1

Information d'application

Indications d'application: 1 : 500 (WB)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 50 μL, of sterile water

Buffer: Serum

Conseil sur la manipulation: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Stock: -20 °C,-80 °C

Stockage commentaire: Store lyophilized/reconstituted at -20°C (short tem, months) or at -80°C (long term, years) , once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Détails sur PSME4

Antigène: PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))

Autre désignation: PA200

Sujet: PA200 (Proteasome activator PA200) is an associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. It also recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response: binds to acetylated histones and promotes degradation of histones. Protein levels increase upon exposure of seedlings to MG132, a specific, potent, reversible, and cell-permeable proteasome inhibitor. Alternative names: Proteasome activator subunit 4, Proteasome activating protein 200.

Poids moléculaire: 202.9 | ca. 200 kDa

ID gène: 820533

UniProt: F4JC97-1

Pathways: DNA Replication, Synthesis of DNA