Recombinant ADRP anticorps (AA 249-376)
Aperçu rapide pour Recombinant ADRP anticorps (AA 249-376) (ABIN7863926)
Antigène
Voir toutes ADRP (PLIN2) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 249-376
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Expression System
- CHO Cells
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Fonction
- Recombinant Adipophilin / Perilipin-2 (Marker of Lipid Accumulation) Antibody
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Specificité
- Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Recombinant fragment (around aa 249-376) of human Adipophilin (ADFP) protein (exact sequence is proprietary)
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- ADRP (PLIN2) (Perilipin 2 (PLIN2))
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Autre désignation
- Adipophilin
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Sujet
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Adipophilin, ADFP, Adipose differentiation-related protein (ADRP), Perilipin-2 (PLIN2)
adrenal gland or cerebellum (IHC).|liver
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Poids moléculaire
- 48kDa
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ID gène
- 123, 3416
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UniProt
- Q99541
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
Antigène
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